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目的探讨米非司酮在治疗胎盘植入过程中的作用及意义,以及胎盘植入保守治疗的价值。方法回顾性分析胎盘植入病例21例,对21例胎盘植入患者采取预防感染、抗贫血、子宫收缩等治疗,并给予米非司酮进行治疗。观察子宫收缩及阴道流血情况,B超复查,未出现大出血。结果 21例胎盘植入患者使用米非司酮保守治疗,第4周B超复查宫腔,除2例仍提示强光团行清宫术外,其余均保守治疗成功,未见任何明显副反应,子宫复旧好。在治疗期间均未出现大量阴道流血,经追踪未发生晚期阴道流血。产后42 d妇科检查子宫恢复正常。结论米非司酮在治疗胎盘植入中有积极作用,治疗过程中未出现子宫复旧不良及大出血,效果满意,给药方便,简单易行,值得临床中推广应用。
Objective To explore the role and significance of mifepristone in the treatment of placenta accreta and the value of conservative treatment of placenta accreta. Methods Twenty-one cases of placenta accreta were retrospectively analyzed. Twenty-one placenta accreta patients were treated with prophylaxis of infection, anti-anemia and uterine contractions, and treated with mifepristone. Observation of uterine contractions and vaginal bleeding, B-ultrasound, did not appear bleeding. Results 21 cases of placenta accreta were treated with conservative treatment of mifepristone, the 4th week of B-ultrasound examination of the uterine cavity, in addition to 2 cases still prompted a bright group mission curettage, the remaining conservative treatment were successful, without any obvious side effects, Uterine good old. No significant vaginal bleeding occurred during the course of treatment and no late vaginal bleeding was observed. 42 days postpartum gynecological examination uterus returned to normal. Conclusion Mifepristone has a positive effect in the treatment of placenta accreta. During the treatment, there is no uterine involution and hemorrhage. The effect is satisfactory and the administration is convenient and simple. It is worth popularizing and applying in clinic.