心房颤动(房颤,AF)是临床上最常见、危害最严重的心律失常之一。目前AF电重构成为人们研究的热点,并取得了初步成果,为临床治疗和预防AF提供了重要的信息。近10年的研究证实,AF电重构的基础就是离子通道重构。因此,本文从离子通道电重构这一角度对AF发病的机制作一综述。 Atrial fibrillation (atrial fibrillation, AF) is one of the most clinically common and most dangerous arrhythmias. At present, AF reconstruction has become a hot research topic and has achieved preliminary results, which provide important information for clinical treatment and prevention of AF. Nearly 10 years of research confirmed that the basis of AF electrical remodeling is ion channel reconstruction. Therefore, this article reviews the pathogenesis of AF from the perspective of ion channel electrical remodeling.