论文部分内容阅读
硝普钠(Natrii Nitroprussidum;Sodium Nitro—Prusside;简称 SNP)是一种特异性血管扩张剂。它作用强烈而迅速,维持时间短暂,一般静滴1—2分钟后即可获得所需要的降压作用,利用不同的滴速可使血压稳定在任何所需要的水平上,停药后1—10分钟内,血压便回升到用药前水平。故有人认为硝普钠是效力最强和作用稳定的降压药。在其它降压药不能取得满意疗效时,改用硝普钠仍然有效。它的主要药理作用是能直接松弛小动脉和小静脉平滑肌,引起血管扩张,降低周围血管阻力和动脉血压,而对植物神经和中枢神经系统无影响。临床试验证明静脉滴注硝普钠对并发高血压脑病、
Sodium nitroprussidum (Sodium Nitro-Prusside; referred to as SNP) is a specific vasodilator. Its role is strong and rapid, maintaining a short time, the general intravenous infusion of 1-2 minutes to obtain the required antihypertensive effect, the use of different drip rate can stabilize blood pressure at any desired level, the withdrawal of 1- Within 10 minutes, blood pressure will rise to pre-medication levels. Therefore, some people think that sodium nitroprusside is the most effective and stable antihypertensive drugs. In other antihypertensive drugs can not be obtained with satisfactory results, the switch to sodium nitroprusside is still valid. Its main pharmacological action is the direct relaxation of the small arteries and venules smooth muscle, causing vasodilatation and reduce peripheral vascular resistance and arterial blood pressure, while the autonomic and central nervous system has no effect. Clinical trials show that intravenous infusion of sodium nitroprusside on hypertensive encephalopathy,