头孢克罗是口服半合成头孢菌素类β-内酰胺类抗生素,对大多数革兰阳性菌和革兰阴性菌有较强的抗菌活性,具有良好的β-内酰胺酶稳定性.本试验旨在上海地区三家主要的儿童医院应用头孢克罗治疗小儿急性细菌性支气管炎轻、中度病例进行疗效评价.1资料和方法1.1病例来源 选自上海第二医科大学新华医院儿内科、上海医科大学儿科医院内科、上海市儿童医院内科门急诊各15例,共45例.1.2入选标准 ①年龄6mo～6a;②性别不限;③发病3d内未用抗生素者;④临床具有发热、咳嗽、流涕、咳痰、咽红、肺部可闻及干性啰音、粗湿啰音或哮鸣音者;⑤WBC+DC升高者.l.3 除外条件 有青霉素、头孢菌素过敏,拟诊上呼吸道感染、哮喘、支气管肺炎、先天畸形,心、肝、肾功能不全者.1.4 轻、中度支气管炎诊断标准 轻度:日常生活不受限制,体温<38℃,WBC>9.O×10~9/L,<12×10~9/L,无明显气促.紫绀.中度:体温<39℃,WBC总数>12×10~9/L,<15×10~9/L,呼吸频率≤30 Cefaclor is oral semi-synthetic cephalosporins β-lactam antibiotics, the majority of Gram-positive bacteria and Gram-negative bacteria have strong antibacterial activity, has good β-lactamase stability .This test Aimed at three major Shanghai Children’s Hospital cefaclor treatment of pediatric acute bacterial bronchitis in mild and moderate cases of efficacy evaluation.1 Materials and Methods 1.1 The source of the cases selected from Shanghai Second Medical University, Xinhua Hospital, Department of Pediatrics, Shanghai Medical 15 cases of internal medicine and emergency department of Shanghai Children’s Hospital, a total of 45 cases .1.2 Selection criteria ① age 6mo ~ 6a; ② gender is not limited; ③ the first three days of antibiotics are not; ④ clinically with fever, cough, Runny nose, sputum, throat, the lungs can be heard and dry rales, rough wet rales or wheeze; ⑤ WBC + DC elevated .l.3 except penicillin, cephalosporin allergy, to be Diagnosis of upper respiratory tract infection, asthma, bronchial pneumonia, congenital malformations, heart, liver, renal insufficiency.1.4 mild and moderate bronchitis diagnostic criteria Mild: daily life is not limited to body temperature <38 ℃, WBC> 9.O × 10 ~ 9 / L, <12 × 10 ~ 9 / L, no obvious Cyanosis promote moderate: temperature <39 ℃, WBC total number of> 12 × 10 ~ 9 / L, <15 × 10 ~ 9 / L, respiratory rate ≤30