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具有免疫激活作用的抗肿瘤天然物质,目前已有很多研究,其中一部分已作为药物用于临床。作者在对米糠、麸子等筛选抗肿瘤活性物质时,发现米糠的热水提取物的多糖部分有很强的抗肿瘤(Saroma—180)作用。将此多糖称为米糠多糖(rice bran saccharide),以下简称为RBS。本文对其制法、理化性质、抗肿瘤作用、对免疫系统的作用以及抗感染作用进行了研究,得到了一些有意义的结果。实验部分 RBS的提取分离: 取市售米糠2 kg,用24号筛除去碎米
Anti-tumor natural substances with immune activation have been studied for many years, and some of them have been used as drugs for clinical use. When the authors screened antitumor active substances such as rice bran and bran, they found that the polysaccharide part of the hot water extract of rice bran has a strong anti-tumor (Saroma-180) effect. This polysaccharide is referred to as rice bran saccharide, hereinafter abbreviated as RBS. In this paper, the preparation methods, physicochemical properties, anti-tumor effects, effects on the immune system, and anti-infective effects were studied and some meaningful results were obtained. Experimental section Extraction and separation of RBS: Take 2 kg of commercially available rice bran and remove broken rice with 24 mesh sieve