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目的 为获得清洁级健康实验小鼠。方法 采用剖腹产净化 ,并结合屏障系统饲养管理 ,连续 10年进行微生物学和寄生虫学的监测。结果 净化后的小鼠严格按照清洁级标准饲养管理 ,能够保证小鼠健康生长 ,均可达到国家二级实验小鼠的水平。结论 普通级实验小鼠经剖腹产净化 ,完善饲养管理条件 ,为达到实验动物的标准化奠定了基础。
The purpose is to obtain a clean level of healthy experimental mice. Methods Caesarean section purification, combined with the barrier system feeding and management, for 10 consecutive years of microbiology and parasitology monitoring. Results The purified mice were kept in strict accordance with the standards of cleanliness, which can ensure the healthy growth of mice and reach the level of the national second-level experimental mice. Conclusion The common-level experimental mice were purified by Caesarean section to improve the feeding and management conditions, which laid the foundation for the standardization of experimental animals.