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目的:探讨葡萄膜炎与可溶性白细胞介素2受体(SIL-2R)的关系。方法:用双抗体夹心ELISA法检测64例活动期葡萄膜炎患者血清中SIL-2R水平,并以61例健康人作为对照组。结果:活动期葡萄膜炎患者血清中SIL-2R水平明显高于健康人。活动期的前葡萄膜炎、中间葡萄膜炎、Behcet病及Vogt-Koyanagi-Harada综合征患者血清中SIL-2R水平无显著性差异。缓解期葡萄膜炎患者血清中SIL-2R水平明显低于活动期。结论:血清中SIL-2R水平与葡萄膜炎病情密切相关。眼科学报1998;14:64—65。
Objective: To investigate the relationship between uveitis and soluble interleukin-2 receptor (SIL-2R). Methods: The serum levels of SIL-2R in 64 patients with active uveitis were detected by double antibody sandwich ELISA and 61 healthy controls were used as control group. Results: The serum levels of SIL-2R in patients with active uveitis were significantly higher than those in healthy people. Active anterior uveitis, intermediate uveitis, Behcet’s disease and Vogt-Koyanagi-Harada syndrome serum levels of SIL-2R no significant difference. Serum levels of SIL-2R in patients with uveitis during remission were significantly lower than those in patients with active uveitis. Conclusion: The level of SIL-2R in serum is closely related to the disease of uveitis. Ophthalmic Science 1998; 14: 64-65.