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目的:分析小汗腺汗孔瘤的临床病理表现。方法:对14例小汗腺汗孔瘤进行光镜观察,并对部分病例作免疫组化染色。结果:发现汗孔瘤是一种特异性的肿瘤类型:(1)肿瘤发生于表皮,部分累及真皮。(2)肿瘤细胞和周围棘细胞境界较清楚。(3)肿瘤细胞巢内可见有护膜内衬的小孔、小管状结构。(4)肿瘤以宽带方式向下延伸。(5)宽带之间的间质水肿、疏松。(6)部分肿瘤延伸达真皮深层者,下方形成有少许透明细胞成分的结节。(7)瘤细胞较棘细胞小,镶嵌排列,部分有细胞间桥。结论:汗孔瘤内有透明细胞成分的小结节为小汗腺汗孔瘤的一种亚型,即真皮内导管瘤。
Objective: To analyze the clinicopathological features of the hypohidrosis gland perspiration. Methods: Fourteen cases of hypohidrosis glandular perineural tumors were observed by light microscopy and immunohistochemical staining was performed in some cases. Results: Khanoma was found to be a specific tumor type: (1) Tumors occur in the epidermis, with some involving the dermis. (2) The state of tumor cells and peripheral prickle cells is clearer. (3) Small pores and small tubular structures with lining of pellicles are visible in the nests of tumor cells. (4) Tumors extend downward in a broadband manner. (5) Interstitial edema and loosening between wide bands. (6) Some tumors extend deeper into the dermis, and there are nodules with a few transparent cell components below. (7) The tumor cells are smaller than the spine cells, mosaic arrangement, part of the intercellular bridge. Conclusion: The small nodules with clear cellular components in the perineural tumors are a subtype of the perineumal perirenal tumors, namely intradermal ductal tumors.