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研究表明，茄链格孢（Ａｌｔｅｒｎａｒｉａｓｏｌａｎｉ）培养滤液中存有抗菌活性物质。采用改进Ｂａｒｔｅｌｓ－ｋｅｉｔｈ方法对该物质进行了提取分离并进行抗菌活性跟踪。对纯品通过熔点测定、元素分析及１Ｈ－ＮＭＲ、１３Ｃ－ＮＭＲ、１Ｈ，１Ｈ－ＣＯＳＹ及ＤＥＰＴ光谱解析，证明该物质为交链孢酸（Ａｌｔｅｒｎａｒｉｃａｃｉｄ）。离体试验结果表明，０．１μｇ／ｍｌ交链孢酸对Ｂｏｔｒｙｔｉｓｃｉｎｅｒｅａ，Ｓｃｌｅｒｏｔｉｎｉａｓｃｌｅｒｏｔｉｏｒｕｍ菌丝生长抑制率分别为６４．３％和７３．６％。Ｍ．Ｉ．Ｃ值≤１００μｇ／ｍｌ。５００μｇ／ｍｌ交链孢酸对Ｂ．ｃｉｎｅｒｅａ分生孢子萌发没有影响，但可明显抑制孢子萌发后芽管的伸长，≥１０μｇ／ｍｌ时可完全抑制Ｓ．ｓｃｌｅｒｏｔｉｏｒｕｍ菌核萌发。活体试验表明，５００μｇ／ｍｌ交链孢酸对黄瓜灰霉病和油菜菌核防治效果分别为８２．７％和８３．３％。
Studies have shown that Alternaria solani (Alternariasolani) culture filtrate antibacterial active substances. The material was extracted and separated by the modified Bartels-keith method and the antibacterial activity was tracked. The pure product was confirmed by melting point analysis, elemental analysis and 1H-NMR, 13C-NMR, 1H, 1H-COZY and DEPT spectroscopy. The result showed that this material was Alternaric acid. The results of in vitro tests showed that the inhibitory rates of 0.1μg / ml streptozotocin on mycelial growth of Botrytis cinerea and Sclerotiniasclerotiorum were 64.3% and 73.6%, respectively. M. I. C value ≤100μg / ml. 500 [mu] g / ml Alternaria acid B to B. Conidiophores cinerea did not affect the germination, but could significantly inhibit spore germination germination tube elongation, ≥ 10μg / ml can be completely inhibited by S. Sclerotiorum sclerotia germination. In vivo tests showed that the effect of 500μg / ml Alternaria acipennis on control of Botrytis cinerea and sclerotinia was 82.7% and 83.3% respectively.