化疗患者最常见的毒性反应是胃肠道反应,如食欲下降、恶心、呕吐等,呕吐严重者可引起患者水、电解质平衡紊乱及营养素缺失,同时更可导致患者精神恐惧影响后期的治疗。目前临床普遍使用5-HT3受体拮抗剂预防和治疗化疗药物,但仍有50%～70%的患者存在不同程度的恶心、呕吐反应。 Chemotherapy patients the most common toxicity is gastrointestinal reactions, such as loss of appetite, nausea, vomiting, severe vomiting can cause patients with water and electrolyte balance disorders and nutrient deficiencies, but also can lead to mental fear of patients with late treatment. At present, 5-HT3 receptor antagonists are commonly used to prevent and treat chemotherapy drugs. However, there are still 50% to 70% of patients with varying degrees of nausea and vomiting.