作者报告2例单纯性汗腺棘皮瘤(Hidroaca-nthoma simplex),并复习有关资料。1956年Smith首先提出本病,至1976年已报告14例(包括作者2例)。发病年龄多数在60～70岁,女性占70％。85％发于下肢,其次是面、腕、胸部。临床表现多为扁平隆起的肿瘤或疣样增生性皮疹,少数为红斑结痂。临床常误诊为表皮内鳞癌、老年疣、基底细胞癌等。病理分良性及恶性两型,14例中良性10例,恶性4例。日本5例中恶性2例,作者认为本病恶性倾向应予重视。肿瘤细胞限于表皮内。良性型肿瘤细胞类似基底细胞,核染色质丰富,胞浆淡红,在核周 The authors reported two cases of simple hidroaca-nthoma simplex and reviewed the data. Smith first proposed this disease in 1956, and in 1976 had reported 14 cases (including the author’s 2 cases). The age of onset is mostly 60 to 70 years old, and women 70%. 85% occurred in the lower limbs, followed by the face, wrist, and chest. The clinical manifestations were mostly flattened tumors or cystic hyperplasia rashes, and a few erythematous scars. Clinical often misdiagnosed as intraepidermal squamous cell carcinoma, senile sputum, basal cell carcinoma. There were two types of benign and malignant pathological types: 10 cases were benign in 14 cases and 4 cases were malignant. There were 2 cases of malignant in 5 cases in Japan. The author believes that the malignant tendency of the disease should be taken seriously. Tumor cells are confined within the epidermis. Benign tumor cells resemble basal cells, with abundant nuclear chromatin, pale red cytoplasm, and at the nuclear periphery