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目的:分析探讨复发性尿路感染患者的细菌检验情况与药敏情况,为临床用药提供重要依据。方法:选取2014年6月-2015年6月本院收治并确诊为复发性尿路感染患者共145例,采集中段尿标本培养并进行细菌检验及药物敏感试验,统计病原菌的分布情况及其耐药性。结果:通过检测共发现菌株145株,其中革兰氏阴性杆菌103株(主要包括大肠埃希菌76株占73.7%、铜绿假单胞菌21株占20.4%、阴沟肠杆菌6株占5.9%);革兰氏阳性球菌42株(主要为肠球菌属9株占21.4%、链球菌属12株占28.6%、金黄色葡萄球菌21株占50%),占29%。尿液感染常见的细菌都对亚胺培南敏感率较高,对三代头胞菌素与喹诺酮类抗生素敏感程度一般,对青霉素类的敏感率低。结论:在复发性尿路感染患者致病菌的检测中发现主要以革兰阴性杆菌为主,不同病原菌对不同抗生素具有不同的敏感性,做好病原菌的检测和药物敏感性检测对指导临床科学用药具有重要意义。
Objective: To analyze the situation of bacterial test and drug susceptibility in patients with recurrent urinary tract infection, and provide an important basis for clinical medication. Methods: A total of 145 patients with recurrent urinary tract infection admitted to our hospital from June 2014 to June 2015 were enrolled in this study. Urine specimens were collected for bacterial test and drug susceptibility test. The distribution of pathogens and their resistance Medicinal properties. Results: A total of 145 strains of Gram-negative bacilli were detected, of which 103 strains of Gram-negative bacilli (including 76 strains of Escherichia coli, 73 strains of Escherichia coli, 20.4% of Pseudomonas aeruginosa strains, 6 strains of Enterobacter cloacae, 5.9% ), 42 strains of Gram-positive cocci (mainly Enterococcus 9, 21.4%, Streptococcus 12, 28.6% and Staphylococcus aureus 21, accounting for 29%). The common bacteria in urinary tract infection are sensitive to imipenem, sensitive to the third generation cephalosporin and quinolone antibiotics, and low sensitivity to penicillins. Conclusion: Gram-negative bacilli are the main pathogens detected in patients with recurrent urinary tract infections. Different pathogens have different sensitivity to different antibiotics, and the detection of pathogenic bacteria and drug sensitivity tests are of great importance to guide the clinical science Medication is of great significance.