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目的加强涂阳肺结核患者的治疗管理,提高2月末痰菌阴转率及疗末治愈率,为现代结核病控制策略提供新的治疗管理模式。方法选取2008年和2009年新发涂阳肺结核患者380例,采用2H3R3Z3E3/4H3R3方案治疗,分为村医和家庭成员督导治疗管理两组。在2月末、6月末进行痰涂片和X线胸片检查,观察治疗效果。结果两组2月末痰菌阴转率均为87%、疗末治愈率>91%,两组治疗效果无明显差别。结论家庭成员督导治疗管理的新发涂阳肺结核患者治愈率>91%,达到国家治愈率85%以上目标,是一种适宜贫困山区肺结核患者的督导治疗管理模式。
Objective To strengthen the management of patients with smear positive pulmonary tuberculosis and improve the rate of sputum negative conversion and cure rate at the end of February, providing a new treatment management mode for the control strategy of modern tuberculosis. Methods 380 new smear-positive pulmonary tuberculosis patients in 2008 and 2009 were selected and treated with 2H3R3Z3E3 / 4H3R3 regimen. The two groups were divided into two groups: village doctors and family members. In late February, late June sputum smear and chest X-ray examination to observe the therapeutic effect. Results At the end of February, the sputum negative conversion rate was 87% in both groups and the cure rate was> 91%. There was no significant difference between the two groups. Conclusions The cure rate of new smear-positive pulmonary tuberculosis patients supervised by family members is more than 91%, reaching the goal of more than 85% of the country’s cure rate. It is a supervised treatment management mode suitable for tuberculosis patients in poor mountainous areas.