尿激酶是一种溶血栓药 ,它能激活体内纤溶酶原转为纤溶酶 ,从而水解纤维蛋白使血栓溶解。我科 1996年 1月至1998年 12月应用大剂量尿激酶静脉溶栓治疗急性脑梗死2 8例 ,疗效较好 ,现报告如下。1　对象和方法1.1　入选标准 :1发病 12 h内 ;2头颅 CT未见相对应的低密度影 ,并除外 Urokinase is a thrombolytic agent that activates plasminogen in vivo to convert plasmin to hydrolyse fibrin to thrombolytic. Our department from January 1996 to December 1998 application of high-dose intravenous urokinase thrombolytic therapy of acute cerebral infarction in 28 cases, the effect is better, are as follows. 1 Subjects and methods 1.1 Inclusion criteria: 1 onset of 12 h; 2 head CT no corresponding low-density shadow, and except