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应用马来丝虫成虫冰冻切片抗原作IEST。233例班氏丝虫患者IgG和IgM阳性率分别为94.0％和82.4％,其中微丝蚴血症者223例,IgG和IgM阳性率分别为94.2％和83.9％;该两种抗体总阳性符合率为96.0％。165名献血员IgG和IgM假阳性率分别为6.1％和1.2％。基本消灭丝虫病地区6～15与1～5岁年龄组的抗体水平无显著性差异,且当地未检出微丝蚴血症者,显示丝虫病传播基本阻断;而丝虫病流行区6～15岁年龄组抗体水平接近高峰,表明当地丝虫病仍在传播。提示以6～15岁年龄组人群特异性抗体水平变化与其他年龄组互相比较,可用于丝虫病流行病学监测。
Application of malayian worm adult frozen section antigen for IEST. The positive rates of IgG and IgM in 233 cases of Bancroftian filariasis were 94.0% and 82.4% respectively, including 223 cases of microfilaremia. The positive rates of IgG and IgM were 94.2% and 83.9% respectively. The rate was 96.0%. The false positive rates of IgG and IgM in 165 donors were 6.1% and 1.2% respectively. There was no significant difference in antibody levels between 6-15 and 1- 5 years old groups in areas where filariasis had basically disappeared, and those with microfilaremia were not found in the area, indicating that the transmission of filariasis was basically blocked. The prevalence of filariasis Antibody levels in the age group of 6-15 years old approached the peak, indicating that local filariasis is still spreading. Prompted 6 to 15 age-group population-specific antibody levels compared with other age groups can be used for epidemiological monitoring of filariasis.