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胎儿巨细胞病毒(CMV)感染是先天感染的首要原因,产母感染通常无症状,但50%可通过胎盘传给胎儿,90%新生儿出生时无症状,因此产前诊断非常重要。本文对7例原发性 CMV 感染进行前瞻性研究,强调用羊水培养分离病毒来进行产前诊断。1988年～1990年对1771例孕妇进行的有关胎儿 CMV 感染危险性的研究中,861例血清学试验阴性(48. 4%),每次产前检查都做血清学检查和对尿、唾液、宫颈分泌物进行 CMV 检查,一旦发现血清学有产生抗体的转化现象,则于孕22周予以超
Fetal cytomegalovirus (CMV) infection is the primary cause of congenital infection. Motherhood infection is usually asymptomatic, but 50% can pass through the placenta to the fetus. 90% of newborns are asymptomatic at birth and prenatal diagnosis is therefore very important. In this paper, 7 cases of primary CMV infection were prospectively studied, emphasizing the use of amniotic fluid culture to isolate the virus for prenatal diagnosis. From 1988 to 1990, 1771 pregnant women conducted a study on the risk of fetal CMV infection. 861 serological tests were negative (48.4%). Serum tests were performed on each prenatal examination and urinalysis was performed on urine, saliva, Cervical secretions for CMV examination, once found serological antibody conversion phenomenon, at 22 weeks pregnant to super