七十年代以来发现了能兴奋胃运动机能的胃动素,并认为释放胃动素的细胞多为肠嗜铬细胞,集中分布于人的十二指肠和上部空肠,以后证实胃底和胃窦部也有这种细胞。并发现了胆囊、结肠。小肠、胃、食管粘膜下和肌层存在着含有胃动素的神经元,甚至在中枢神经系统也有含胃动素的神经元。胃动素不但有刺激胃蛋白酶分泌的功能,而且有轻度刺激重碳酸盐和蛋白分泌而影响胰腺外分泌功能,有抑制促胰泌素的胰腺分泌作用。胃动素可引起胃肠道平滑肌的剧烈收缩,其作用强度为乙酰胆硷的50倍左右,以胃和十二指肠平 Since the seventies mothers have been found to be able to excite gastric motor motility, mothers and that the release of motilin cells are mostly enterochromaffin cells, concentrated in the human duodenum and upper jejunum, confirmed after the stomach and stomach Sinus also has this kind of cell. And found the gallbladder, colon. There are motoneuron-containing neurons in the small intestine, stomach, esophageal submucosa and muscularis, and motilin-containing neurons in the central nervous system. Motilin not only has the function of stimulating pepsin secretion, but also mildly stimulates the secretion of bicarbonate and protein and affects the exocrine function of the pancreas, and inhibits the secretion of secretin by the pancreas. Motilin can cause severe contraction of gastrointestinal smooth muscle, the role of the intensity of acetylcholine about 50 times the stomach and duodenum level