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分析报道2例典型的海洛因致急性肾衰竭患者。均为男性,平均年龄31岁,均因静脉注射海洛因后出现非创伤性横纹肌溶解症、急性肾衰竭、肝功能损害和贫血。其中1例病情较重,昏迷10h,持续少尿20d,同时伴有双下肢筋膜间隙综合征,严重肝功能和血液系统损害。1例予以血液透析滤过5次,另1例予以连续性血液净化23次及对症支持治疗后,均痊愈出院。临床观察显示,海洛因致急性肾衰竭在临床上具有自身的特点,主要表现为非创伤性横纹肌溶解症、急性肾衰竭、肝功能损害和贫血。连续性血液净化是治疗重症海洛因致急性肾衰竭的有效方法。
Analysis reported 2 cases of typical heroin-induced acute renal failure patients. All men, mean age 31 years old, developed noninvasive rhabdomyolysis, acute renal failure, impaired liver function, and anemia after intravenous injection of heroin. One case of serious illness, coma 10h, sustained oliguria 20d, accompanied by double lower extremity fascia gap syndrome, severe liver function and blood system damage. 1 case was hemodiafiltration 5 times, the other 1 case of continuous blood purification 23 times and symptomatic and supportive treatment, were cured. Clinical observations show that heroin-induced acute renal failure has its own clinical features, mainly non-traumatic rhabdomyolysis, acute renal failure, liver damage and anemia. Continuous blood purification is an effective treatment for severe heroin-induced acute renal failure.