1临床资料1．1一般资料吉林市儿童医院1978年2月至1996年4月收治新生儿病人6652例，患硬肿症者792例，占11．9％。6652例中早产儿病人534例，急硬肿症232例，占早产儿病人的43．35％。本组对2例中男性174例，女性58例，男女之比为3：1。发病日龄与入院时体重见表1。发病时间与 1 Clinical data 1.1 General Information Jilin Children’s Hospital February 1978 to April 1996 6652 cases of neonates admitted to patients with scleroderma 792 cases, accounting for 11.9%. Among the 6652 cases, 534 were premature infants, 232 were acute sclerosis and 43.35% were premature infants. The group of 2 patients, 174 were male, 58 females, male to female ratio of 3: 1. The age of onset and weight at admission are shown in Table 1. Onset time and