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本文搜集我国自1965年以来国内文献报告的27例 Zollinger-Ellison 综合征,均有严重溃疡病史,其中合并出血19例,穿孔16例,腹泻10例,幽门梗阻4例。大部分溃疡为吻合口溃疡,其次为空肠溃疡、十二指肠溃疡和胃多发溃疡。血清胃泌素含量135～4000pg/ml,平均1535±452。胃液分析 BAO/MAO 0.46～2.6,平均0.82。27例中胰腺肿瘤20例,其中恶性占45%,多发性内分泌腺瘤Ⅰ型2例,具有多激素分泌性。全胃或肿瘤切除术的预后较好。
This article collected 27 cases of Zollinger-Ellison syndrome reported in domestic literature since 1965 in our country, all of which have severe ulcers history, including 19 cases of combined hemorrhage, 16 cases of perforation, 10 cases of diarrhea, and 4 cases of pyloric obstruction. Most of the ulcers were anastomotic ulcers, followed by jejunal ulcers, duodenal ulcers, and multiple gastric ulcers. Serum gastrin content 135 ~ 4000pg/ml, an average of 1535 ± 452. Gastric fluid analysis BAO/MAO 0.46 ~ 2.6, an average of 0.82. 27 cases of pancreatic tumors in 20 cases, including malignant 45%, 2 cases of multiple endocrine adenomas type I, with multiple hormone secretion. The prognosis for total stomach or tumor resection is better.