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目的:观察运脾解毒汤治疗非酒精性脂肪性肝炎的临床疗效。方法:将122例非酒精性脂肪性肝炎患者随机分为治疗组和对照组。治疗组采用经验方运脾解毒汤治疗,对照组采用易善复胶囊治疗,疗程3月。观察并比较2组患者治疗前后的症状、体征和肝功能、血脂等变化。结果:总有效率治疗组为90.22%,对照组为76.67%,2组比较,差异有显著性意义(P<0.05)。治疗组治疗后各肝功能指标均明显改善,与治疗前比较,差异均有非常显著性意义(P<0.01);2组治疗后比较,差异也有显著性意义(P<0.05)。治疗组治疗后各血脂指标均明显改善,与治疗前比较,差异有显著性或非常显著性意义(P<0.05,P<0.01);2组治疗后比较,差异也有显著性意义(P<0.05)。结论:运脾解毒汤治疗非酒精性脂肪性肝炎疗效肯定。
Objective: To observe the clinical efficacy of Yunpi Jiedu Decoction in the treatment of non-alcoholic steatohepatitis. Methods: 122 cases of non-alcoholic steatohepatitis were randomly divided into treatment group and control group. The treatment group adopted the experience of prescription spleen detoxification soup treatment, the control group with Yi Shan Fu capsule treatment, treatment in March. The changes of symptoms, signs, liver function and blood lipids in the two groups before and after treatment were observed and compared. Results: The total effective rate was 90.22% in the treatment group and 76.67% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the indexes of liver function in the treatment group were significantly improved, with significant difference compared with those before treatment (P <0.01). There was also significant difference between the two groups after treatment (P <0.05). After treatment, the levels of each lipid in the treatment group were significantly improved (P <0.05, P <0.01), and the difference was also significant (P <0.05) ). Conclusion: Yunpi Jiedu Decoction in the treatment of non-alcoholic steatohepatitis sure effect.