论文部分内容阅读
目的 探讨 2型糖尿病 (type 2diabetesmellitus ,T2DM )患者血管内皮生长因子 (vascularendothelialgrowthfactor,VEGF)与糖化血红蛋白 (HbA1C)的关系。方法 对 15 8例T2DM患者进行血清VEGF和HbA1C检测及眼底检查。结果 糖尿病视网膜病变 (DR)患者组血清VEGF和HbA1C水平显著高于糖尿病无视网膜病变组。在DR轻、中、重三组中 ,VEGF水平随病变的加重呈升高趋势。结论 血清VEGF可作为T2DM患者并发视网膜病变及其他微血管病变的指标。血清VEGF与HbA1C在DR的早期诊断及反映DR病变程度上 ,两者可能存在一致性
Objective To investigate the relationship between vascular endothelial growth factor (VEGF) and glycosylated hemoglobin (HbA1C) in type 2 diabetes mellitus (T2DM). Methods Serum levels of VEGF and HbA1C in 15 8 T2DM patients and their fundus examination were examined. Results The levels of serum VEGF and HbA1C in patients with diabetic retinopathy (DR) were significantly higher than those without diabetic retinopathy. The level of VEGF increased with the increase of the lesion in the three groups of mild, moderate and severe DR. Conclusion Serum VEGF can be used as a marker of retinopathy and other microangiopathy in T2DM patients. Serum VEGF and HbA1C in the early diagnosis of DR and reflect the extent of DR lesions, the two may exist consistency