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目的:探讨甲状腺功能亢进(甲亢)患者机体内血脂代谢、甲状腺激素水平相关性。方法:将我院2015年12月到2016年12月收治的150例患者作为研究对象,分析治疗前后患者血脂水平与甲状腺激素(TH)水平相关性。结果:与健康组对比,甲亢患者游离甲状腺素(FT4)、游离三碘甲状腺原氨酸(FT3)水平明显升高,促甲状腺激素水平(TSH)降低,差异具有统计学意义(P<0.05);三酰甘油(TG)、载脂蛋白A(apoAI)、总胆固醇(TC)、高密度脂蛋白胆固醇(LDL-C)与载脂蛋白B(apoB)均有所下降,差异具有统计学意义(P<0.05);低密度脂蛋白胆固醇(HDL-C)无显著变化,不具有统计学意义(P>0.05)。结论:甲状腺激素与脂类代谢具有很大联系,临床上可根据血脂水平帮助临床诊治工作的开展,给疾病分析与控制提供临床参考指标。
Objective: To investigate the correlation between serum lipid metabolism and thyroid hormone in patients with hyperthyroidism (hyperthyroidism). Methods: A total of 150 patients admitted from December 2015 to December 2016 in our hospital were enrolled in this study. The correlation between serum lipids and thyroid hormone (TH) levels was analyzed before and after treatment. Results: Compared with healthy group, the level of FT4 and FT3 in patients with hyperthyroidism was significantly increased and the level of thyroid stimulating hormone (TSH) was decreased, the difference was statistically significant (P <0.05) ; TG, apoAI, TC, LDL-C and apoB decreased, the difference was statistically significant (P <0.05). There was no significant difference in HDL-C (P> 0.05). Conclusions: Thyroid hormones are closely linked with lipid metabolism. Clinically, according to the level of blood lipids, clinical diagnosis and treatment can be carried out to provide clinical reference indexes for disease analysis and control.