丙型肝炎病毒(hepatitis C virus,HCV)是一种黄病毒属的单股正链嗜肝RNA病毒,是引起慢性肝病的主要病原体。机体在抗HCV感染免疫过程中,固有免疫(innate immunity)与适应性免疫(adaptive immunity)相互依赖,互相协作。固有免疫通过诱生各类干扰素、激活NK细胞,在病毒感染早期限 Hepatitis C virus (HCV) is a single-stranded, positive-chain, hepadnavirus of the genus Flaviviridae that is the major causative agent of chronic liver disease. In the body’s immune response to HCV infection, innate immunity and adaptive immunity are interdependent and cooperate with each other. Intrinsic immunity induces NK cells by inducing various types of interferons and is limited in the early stages of viral infection