体外测定了２４例支气管哮喘急性发作期病人和３４例健康人外周血单核／巨噬细胞的ＡＤＣＣ效应及非特异性吞噬功能。结果表明：自然状态下，哮喘病人单核／巨噬细胞ＡＤＣＣ作用及非特异性吞噬功能与健康对照无差异；但经ＬＰＳ活化后，哮喘组ＡＤＣＣ效应明显高于健康对照组，而非特异性吞噬功能减弱，低于健康对照，两者差异均显著（Ｐ＜０．０５）。提示：哮喘病人单核／巨噬细胞ＡＤＣＣ作用增高可能参与了病变局部变态反应性炎症病灶的形成。 ADCC and nonspecific phagocytosis of peripheral blood monocytes / macrophages in 24 patients with acute exacerbation of bronchial asthma and 34 healthy controls were measured in vitro. The results showed that ADCC and nonspecific phagocytosis of monocytes / macrophages in asthmatic patients were not different from healthy controls. However, the ADCC effect in asthmatic group was significantly higher than that in healthy controls after LPS activation, while non-specific phagocytosis Weakened, lower than the healthy control, the difference was significant (P <0.05). It is suggested that the increased ADCC of monocytes / macrophages in asthmatic patients may be involved in the formation of focal allergic inflammation.