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目的:观察胃苏颗粒佐治肝胃不和证幽门螺杆菌感染相关性消化性溃疡临床疗效。方法:将82例患者随机分为2组各41例,对照组给予枸橼酸铋钾、奥美拉唑、呋喃唑酮治疗;观察组在对照组基础上给予胃苏颗粒。比较2组的临床疗效、Hp根除率和复发率。结果:对照组溃疡愈合率为68.3%,总有效率为75.6%。观察组溃疡愈合率为73.2%,总有效率为95.1%。2组溃疡愈合率比较,差异无显著性意义(P>0.05)。2组总有效率比较,差异有显著性意义(P<0.05)。对照组Hp根除率87.8%,观察组Hp根除率为90.2%,2组Hp根除率比较,差异无显著性意义(P>0.05)。观察组复发率为5.13%(2/39),对照组复发率为29.0%(9/31),2组比较,差异有显著性意义(P<0.05)。结论:胃苏颗粒佐治肝胃不和证幽门螺杆菌感染相关性消化性溃疡疗效确切。
Objective: To observe the clinical efficacy of Weisu Granule in treating hepatomegaly and non-Helicobacter pylori associated peptic ulcer. Methods: 82 patients were randomly divided into two groups of 41 cases, the control group was given bismuth potassium citrate, omeprazole, furazolidone treatment; the observation group was given on the basis of the control group of stomach particles. The clinical efficacy, Hp eradication rate and recurrence rate were compared between the two groups. Results: The control group ulcer healing rate was 68.3%, the total effective rate was 75.6%. Observation group ulcer healing rate was 73.2%, the total effective rate was 95.1%. There was no significant difference between the two groups in the healing rate of ulcer (P> 0.05). The total effective rate of 2 groups, the difference was significant (P <0.05). The control group Hp eradication rate was 87.8%, observation group Hp eradication rate was 90.2%, two groups of Hp eradication rate, the difference was not statistically significant (P> 0.05). The recurrence rate was 5.13% (2/39) in the observation group and 29.0% (9/31) in the control group. There was significant difference between the two groups (P <0.05). Conclusion: Weisu granule adjuvant liver and stomach syndrome and Helicobacter pylori infection related peptic ulcer curative effect is exact.