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根据国际纯化学和应用化学联合会(IUPAC)的命名原则,含有手性中心的手性分子的立体构型以R/S表示。对于一个含有手性碳原子的分子,要确定它属于R型或S型。通常采用的方法主要包括两个步骤:首先,根据“次序规则”将手性碳原子上连有的四个不相同的原子或原子团按其先后位次排列,其次是将该分子在纸面上的二维空间投影式凭人们想象转变为三维空间的立体模型,而后再确定其构型。例如:确定下列手性分子的构型
According to the nomenclature of the International Union of Pure and Applied Chemistry (IUPAC), the stereoconfiguration of a chiral molecule containing a chiral center is represented by R / S. For a molecule containing a chiral carbon, make sure that it belongs to the R or S type. The commonly used method mainly consists of two steps: First, according to the “rules of order” will chiral carbon atoms linked to four different atoms or atomic groups in its order of priority, followed by the molecule on the paper The projection of two-dimensional space by the people’s imagination into three-dimensional model of the three-dimensional space, and then determine its configuration. For example: Determine the configuration of the following chiral molecules