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一氧化氮(NO)是一种内源性血管扩张剂,哺乳动物的内皮细胞可通过左旋精氨酸NO途径合成,能选择性扩张肺血管,并迅速与血红蛋白结合而失活;在新生儿持续性肺动脉高压、先天性心脏病肺动脉高压、成人型呼吸窘迫综台征的治疗中有肯定疗效。但高浓度NO吸入可致肺损伤,CDC(美国疾病控制中心——编者注)推荐吸入气中NO_2不超过5ppm(8小时内)。本研究试图通过NO吸入的监测制定一种NO的安全吸
Nitric oxide (NO) is an endogenous vasodilator. Endothelial cells of mammals can be synthesized by L-arginine NO pathway, selectively expanding pulmonary vessels and rapidly inactivating hemoglobin. In neonates Persistent pulmonary hypertension, congenital heart disease pulmonary hypertension, adult respiratory distress syndrome in the treatment of certain effects. However, inhalation of high concentrations of NO can cause lung damage. CDC (US Centers for Disease Control - Editor’s note) recommends no more than 5 ppm of NO 2 in inhaled air (within 8 hours). This study attempts to establish a safe inhalation of NO by monitoring NO inhalation