论文部分内容阅读
[目的]观察沉香降气散联合雷贝拉唑与伊托必利治疗反流性食管炎疗效。[方法]使用随机平行对照方法,将62例住院患者按就诊顺序编号简单随机分为两组。对照组31例雷贝拉唑10mg/次,2次/d,晨起及睡前口服;伊托必利50mg/次,3次/d,餐前30min口服。治疗组31例沉香降气散(沉香4g后下,砂仁5g后下,香附10g,川楝子15g,玄胡索10g,吴茱萸4g,黄连6g,刺猬皮15g,太子参12g),1剂/d,水煎200m L,早晚温服;雷贝拉唑与伊托必利治疗同对照组。连续治疗6周为1疗程。观测临床症状、血液生化指标(血常规、尿常规、大便常规、心电图、肝肾功能)、胃镜、不良反应。治疗1疗程,判定疗效。[结果]临床疗效治疗组显效16例,有效13例,无效2例,总有效率93.55%。对照组显效6例,有效16例,无效9例,总有效率70.97%。治疗组疗效优于对照组(P<0.05)。胃镜评价治疗组显效13例,有效15例,无效3例,总有效率90.32%。对照组显效9例,有效10例,无效12例,总有效率61.29%。治疗组疗效优于对照组(P<0.05)。[结论]沉香降气散联合雷贝拉唑与伊托必利治疗反流性食管炎疗效显著,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Shenxiang Xiaoyaosan combined with rabeprazole and itopride on reflux esophagitis. [Methods] Using randomized parallel control method, 62 inpatients were randomly divided into two groups according to the order of visiting doctor. Control group, rabeprazole 31mg 10mg / time, 2 times / d, morning and bedtime oral; itopride 50mg / time, 3 times / d, 30min oral meal. The treatment group, 31 cases of alopecia areata (4g after the next under the incense, Amomum under 5g, Cyperus rotundus 10g, Toosendan 15g, Xuan Hu Suo 10g, Evodia 4g, Coptis 6g, hedgehog skin 15g, heterophylla 12g), 1 Agent / d, decoction 200m L, morning and evening warm clothes; rabeprazole and itopride treatment with the control group. Continuous treatment of 6 weeks for a course of treatment. Clinical symptoms, blood biochemical indicators (blood, urine, stool, electrocardiogram, liver and kidney function), endoscopy, adverse reactions were observed. Treatment of a course of treatment to determine the efficacy. [Result] The clinical curative effect group was markedly effective in 16 cases, effective in 13 cases and ineffective in 2 cases, the total effective rate was 93.55%. In the control group, 6 cases were markedly effective, 16 cases were effective, 9 cases were ineffective, and the total effective rate was 70.97%. The treatment group was better than the control group (P <0.05). Gastroscopy evaluation group markedly effective in 13 cases, effective in 15 cases, 3 cases, the total effective rate was 90.32%. In the control group, 9 cases were markedly effective, 10 cases were effective and 12 cases were ineffective. The total effective rate was 61.29%. The treatment group was better than the control group (P <0.05). [Conclusion] Shenxiang Jiangqi combined with Rabeprazole and Itopride has a significant curative effect on reflux esophagitis without serious adverse reactions, which deserves promotion.