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由于长期投喂低蛋白、高脂肪、高糖类和缺维生素的饵料，会造成罗非鱼脂肪代谢障碍，脂肪大量储积，导致鱼体肥胖，抗病能力低下。患肥胖症的罗非鱼呈全身性脂肪细胞增生、脂肪浸润，特别是腹腔内的脂肪组织及脏器周围的脂肪组织显著增加。患鱼腹腔内脂肪可达体重的5％～8％。
Due to long-term feeding of low protein, high fat, high carbohydrate and vitamin-deficient diet, can cause tilapia lipid metabolism disorders, fat accumulation, resulting in obesity, disease resistance. Tilapia suffering from obesity showed systemic adipocyte hyperplasia, fat infiltration, especially in the peritoneal adipose tissue and organs around the adipose tissue increased significantly. Fish suffering from intra-abdominal fat up to 5% to 8% of body weight.