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文章应用文献计量分析手段,对《外台秘要》中涉及细辛的汤剂进行整理,总结共97首汤剂中使用细辛,对其不同剂量频次分类整理,得出细辛的日常用剂量为13.8g、27.6g和41.4g,剂量范围在6.9～69g,明显高于《中国药典》对细辛用量范围的规定。文章分析《外台秘要》汤剂中应用细辛剂量明显大于《中国药典》的规定,原因是唐代以前医家认为细辛无毒,并且唐代以前单味中药用量普遍大于现代用量规定;应用细辛的剂量范围较广,可能与《外台秘要》不同医家的中药用量经验有关。本研究为细辛用量研究提供文献学的依据,为《中国药典》及《中药学》教材中细辛剂量的标准设定提供参考。
In this paper, we use the bibliometric analysis method to sort out the asarum-related decoctions in “The Essentials of the Extra-table”, summarize the total amount of asarum in 97 decoctions, The dosage of 13.8g, 27.6g and 41.4g, the dosage range of 6.9 ~ 69g, significantly higher than the “Chinese Pharmacopoeia” asarum dosage range requirements. The article analyzes that the dose of Asarum applied in Decoction of Guantai Capsule is obviously larger than that stipulated in Chinese Pharmacopoeia. The reason is that before the Tang Dynasty, physicians thought Asarum was non-toxic, and the dosage of single Chinese herb was generally larger than that of modern dosage before Tang Dynasty. The dose of Asarum is widely used, which may be related to the experience of traditional Chinese medicine used by different physicians in “The Secret of Taiwan”. In this study, we provided the basis of philology for the study of asarum dosage, and provided references for the standard setting of asarum dose in the teaching materials of “Chinese Pharmacopoeia” and “Chinese Pharmacology”.