过敏性紫癜(HSP)是以小血管炎为主要病变的系统性血管炎,其特点表现为非血小板减少性紫癜、腹痛、关节痛、便血、血尿及蛋白尿。抗磷脂综合征(APS)是指临床表现为反复的血栓形成、习惯性流产和血小板减少症,并伴有抗磷脂抗体持续阳性的综合征。APS和HSP均为多系统疾病,二者均可累及系统或脏器,且已有报道APS和HSP可同时发生在同一个体,但二者的关系尚不清楚。现就HSP并APS进行文献综述,并分析其可能机制。 Henoch-Schonlein Purpura (HSP) is a systemic vasculitis that is characterized by small vasculitis and is characterized by non-thrombocytopenic purpura, abdominal pain, joint pain, hematochezia, hematuria, and proteinuria. Antiphospholipid syndrome (APS) refers to the clinical manifestations of repeated thrombosis, habitual abortion and thrombocytopenia, accompanied by persistent anti-phospholipid antibodies syndrome. Both APS and HSP are multisystem diseases, both of which can affect the system or organs. It has been reported that APS and HSP can occur simultaneously in the same individual, but the relationship between them is not yet clear. Now on the HSP and APS literature review, and analyze its possible mechanism.