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异菸肼自1950年综合制成,已被临床广泛应用于治疗肺结核;咸认为该药易于制造,价值低廉,成为抗痨药中较理想药物之一。关于其毒性反应,一般多认为该药对心、肝、肾等,用普通治疗剂量,无何不良反应。其付作用多见于神经系统,如头痛、失眠、眩晕、下肢抽搐、神志不清、运动机能减退、多发性神经炎或胃肠官能紊乱症等。关于该药对肝脏损害之报导,国内有王中坚氏异菸肼出现黄疸一例;杨天楹氏报告急
Isoniazid synthesized since 1950, has been widely used in clinical treatment of pulmonary tuberculosis; salty that the drug is easy to manufacture, low value, anti-drug drugs to become one of the more ideal. About its toxicity, the general thought that the drug on the heart, liver, kidney, etc., with the general treatment dose, no adverse reactions. Its role more common in the nervous system, such as headache, insomnia, dizziness, lower extremity convulsions, confusion, motor impairment, polyneuritis or gastrointestinal disorders. About the drug on the liver damage reported, there is Wang Jianzhong isoniazid jaundice a case;