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类风湿关节炎是一种自身免疫性疾病。诊断该病时常以血清类风湿因子(RF)试验作为辅助检查,但其阳性反应并非类风湿关节炎所独有,如肝炎、50％的原发性干燥综合征、某些免疫性疾病(如全身性红斑狼疮等)、传染性单核细胞增多症及5～7％正常人群的RF也可能呈阳性反应。但在以上患者的关节滑液中RF不会呈阳性,本文检测了55例关节炎患者的血清和关节滑液类风湿因子,现将结果报告如下。 资料与方法:本组55例关节炎患者,男21例,女34例;年龄25～65岁,均排除了肝炎、红细胞性心内肌炎、黑热病、50％的原发性干燥综合征及某些免疫性疾病(如全身性红斑狼疮等)、传染性单核细胞增多症。全部病例均于上午8时抽取空腹血2ml,离心后行血清RF实验;抽关节液0.5～1ml做滑液RF试验。将滑液(或血清)放入56℃孵箱中30分钟灭
Rheumatoid arthritis is an autoimmune disease. Serum rheumatoid factor (RF) tests are often used as adjunctive exams to diagnose the disease but their positive response is not unique to rheumatoid arthritis, such as hepatitis, 50% of primary Sjögren’s syndrome, certain autoimmune diseases such as Systemic lupus erythematosus, etc.), infectious mononucleosis and 5-7% of the normal population of RF may also be positive. However, in these patients with synovial fluid RF will not be positive, the paper examined 55 cases of arthritis in patients with serum and synovial rheumatoid factor, the results are reported as follows. Materials and Methods: The group of 55 patients with arthritis, 21 males and 34 females; aged 25 to 65 years, were ruled out of hepatitis, erythrocyte endocarditis, kala-azar, 50% of the primary Sjogren’s syndrome and Some immune diseases (such as systemic lupus erythematosus, etc.), infectious mononucleosis. All cases were taken at 8 o’clock in the morning fasting blood 2ml, after centrifugation serum RF experiments; pumping joint fluid 0.5 ~ 1ml do synovial fluid RF test. Slide synovial fluid (or serum) into a 56 ° C incubator for 30 minutes