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目的 探讨预先的TIA是否对后继脑梗死有保护作用。方法 对 6 6 3例脑梗死患者 ,按照是否预先发生同侧的TIA及其持续时间分为TIA短于 2 0min组 ,TIA 2 0~ 6 0min组和无TIA组 ,并于病程 1个月时对各组进行生活能力评分 ,评定预后 ,分析预后与TIA持续时间、发作次数及TIA与脑梗死间隔时间的关系。结果 脑梗死前有TIA发作短于 2 0min、发作 2~ 3次与脑梗死间隔不超过 1周者 ,其预后明显好于无TIA者 (P <0 .0 1或 0 .0 5 )。结论 脑梗死前发生的同侧TIA可能产生缺血耐受现象 ,对后继发生的脑梗死起保护作用。
Objective To investigate whether pre-TIA has a protective effect on subsequent cerebral infarction. Methods Sixty-three patients with cerebral infarction were divided into TIA of less than 20 min, TIA 20 min to 60 min and no TIA according to whether the pre-occurrence of ipsilateral TIA and its duration were performed. At the time of 1 month The living ability of each group was scored, the prognosis was evaluated, the prognosis and duration of TIA, the number of seizures and the relationship between TIA and cerebral infarction interval were analyzed. Results Before TIA, the onset of TIA was shorter than 20 minutes, and the episodes of 2 to 3 episodes of cerebral infarction were less than 1 week. The prognosis was significantly better than those without TIA (P <0.01 or 0.05). Conclusion The ipsilateral TIA occurred before cerebral infarction may cause ischemic tolerance, which may protect the subsequent cerebral infarction.