应用毛细管区带电泳法，对伸筋丹胶囊中的士的宁和马钱子碱成分进行了分离研究。采 用ｐＨ＝６．０的０．２ ｍｏｌ／Ｌ．ｔｒｉｓ－磷酸溶液作为缓冲液；运行电压２０ ｋＶ；检测波长为２６０ｎｍ，被测成 分可得到较好分离。用内标法测定其含量，结果表明，在 ０．０２～０．１５ ｍｇ／ｍＬ范围内，士的宁和马 钱子碱均与内标峰面积之比呈良好线性关系，平均回收率分别为９５．１％（ＲＳＤ＝２．８％）和９６．４％ （ＲＳＤ＝３．０ ％）。 Separation of strychnine and strychnine components in Shenjindan Capsules was studied by capillary zone electrophoresis. Use 0.2 mol/L with pH=6.0. The tris-phosphate solution was used as a buffer; the operating voltage was 20 kV; the detection wavelength was 260 nm, and the measured components were well separated. The content was measured by the internal standard method. The results showed that in the range of 0.02 to 0.15 mg/mL, the ratio of strychnine and strychnine to the peak area of ​​the internal standard showed a good linear relationship, and the average recovery rate was It was 95.1% (RSD = 2.8%) and 96.4% (RSD = 3.0%).