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目的对肠炎沙门菌(Salmonella enteritidis,S.E)感染特征进行初步分析。方法通过对2012年-2013年食源性疾病进行主动监测和相关因素调查,并对阳性检出菌株进行双酶切PFGE分型、抗生素敏感试验。结果 2012年-2013年徐州地区哨点医院病例S.E感染率为6.15%,明显高于既往3年的水平(0.79%),差异有统计学意义(χ2=15.5,P<0.01)。可疑食品污染率为3.70%,鸡专项样品污染率为6.94%。42株阳性检出菌中,15株人源菌株和6株环境来源菌株聚类相似程度>90%。烧烤食品和鸡源性分离菌株与人源株的聚类相似程度达到100%。阿莫西林/克拉维酸、头孢拉定、环丙沙星对21株菌的体外敏感率为100%。萘啶酮酸的耐药率最高,为38.1%(8/21)。结论徐州地区可能存在共同暴露来源的S.E流行。
Objective To analyze the characteristics of Salmonella enteritidis (S.E.) infection. Methods Based on the investigation of foodborne diseases from 2012 to 2013 and related factors, the positive isolates were double-digested PFGE typing and antibiotic sensitivity test. Results The S.E. infection rate of sentinel hospital in Xuzhou from 2012 to 2013 was 6.15%, which was significantly higher than that of the past three years (0.79%) (χ2 = 15.5, P <0.01). Suspicious food contamination rate was 3.70%, chicken specific sample contamination rate was 6.94%. Of the 42 positive detection strains, 15 strains of human strains and 6 strains of environment-origin bacteria clustered similar degree> 90%. The degree of similarity between the grilled foodstuffs and the chicken-derived isolates was similar to that of human strains by 100%. In vitro susceptibility of amoxicillin / clavulanic acid, cefradine and ciprofloxacin to 21 strains was 100%. Nalidixic acid had the highest resistance rate of 38.1% (8/21). Conclusion There may be a common source of S.E epidemic in Xuzhou area.