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气道-消化道乳头状瘤病(ADTP)治疗的方法虽然很多,有药物、手术和物理疗法,但常常复发,根治率低。本文回顾了19例年龄1.5～68岁,大部分是于内窥镜反复钳除直至复发停止的ADTP病例,其中4例有迅速复发的喉和/或气管支气管乳头状瘤的成年患者用BCG行免疫治疗(2例未完成治疗),2例按计划治疗者效果良好。BCG为灭毒的结核分支杆菌株,已证明它有较大的免疫作用:增进网状内皮系统的功能;增强抗体反应;使多种抗原的迟发型超敏皮肤反应增强;促进巨噬细胞的代谢和吞噬作用及灭癌细胞的能力;增强抗感染力;增强抗免疫麻痹;释放干扰素。在实体瘤和白血病的治疗中可见由上
Although many methods of treatment of airways - gastrointestinal papillomatosis (ADTP), there are drugs, surgery and physical therapy, but often relapse, the cure rate is low. In this review, we reviewed 19 ADTP cases aged 1.5 to 68 years old, most of whom underwent end-to-end cesarean section until recurrence. Four of the adult patients with recurrent laryngeal and / or tracheobronchial papilloma were treated with BCG Immunotherapy (2 cases did not complete the treatment), 2 cases of scheduled treatment were effective. BCG is a virulent strain of Mycobacterium tuberculosis that has been shown to have a greater immunogenicity: to enhance the function of the reticuloendothelial system; to enhance the antibody response; to enhance the delayed type hypersensitivity skin reaction of multiple antigens; to promote macrophage-derived Metabolism and phagocytosis and the ability to eliminate cancer cells; enhance anti-infective power; enhance anti-immune paralysis; release of interferon. Visible in the treatment of solid tumors and leukemia