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目的了解重型脑血管病患者院内肺部感染(NP)的病原菌分布及对抗生素的敏感性。方法选取吉林市第二中心医院ICU病房45例重型脑血管病患者,取呼吸道分泌物进行培养及药敏试验,并进行病原学分析。结果 45例脑血管病患者呼吸道分泌物共培养出病原菌11种、163株,出现频率位居前两位的菌株为金黄色葡萄球菌、铜绿假单胞菌。G-菌对亚胺培南最敏感,G+菌普遍对万古霉素敏感。结论重型脑血管病患者NP的主要病原菌是金黄色葡萄球菌和铜绿假单胞菌。金黄色葡萄球菌对万古霉素敏感;而铜绿假单胞菌对丁胺卡那霉素及左氧氟沙星较敏感,可作为临床的经验性用药。
Objective To understand the distribution of pathogenic bacteria in hospital with pulmonary infection (NP) in patients with severe cerebrovascular disease and its sensitivity to antibiotics. Methods Forty-five patients with severe cerebrovascular disease in ICU ward of Second Central Hospital of Jilin City were selected for culture and drug sensitivity test of respiratory secretions, and the etiological analysis was conducted. Results The respiratory secretions from 45 patients with cerebrovascular diseases co-cultured 11 kinds of pathogenic bacteria and 163 strains. The most frequently occurring strains were Staphylococcus aureus and Pseudomonas aeruginosa. G-bacteria are the most sensitive to imipenem, G + bacteria are generally susceptible to vancomycin. Conclusion The main pathogens of NP in patients with severe cerebrovascular disease are Staphylococcus aureus and Pseudomonas aeruginosa. Staphylococcus aureus is sensitive to vancomycin, while Pseudomonas aeruginosa is more sensitive to amikacin and levofloxacin, and can be used as a clinical empirical medicine.