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本实验在阿霉素大鼠皮肤伤口模型上,观察中药珠香散的促伤口愈合作用机理。珠香散以麝香、珍珠粉为主,具有生肌固皮的作用。实验分为4组:(1)对照组。(2)模型组。(3)模型+珠香散组。(4)模型+生肌散组。实验于手术前4日尾静脉注射阿霉素8mg/kg,然后全厚皮切除直径1.5cm的皮肤,无菌纱布及0.25g/cm~2药物外敷,隔日换药1次。实验发现,珠香散及生肌散两组在实验第4天伤口面积比模型组增大,分别为2.19±0.58cm~2,2.04±0.43cm~2,疮面分泌物增多,而模型组为1.63±0.51cm~2;实验第8天珠香散组伤口面积明显减小,为0.51±0.19cm~2,而模型组为
This experiment was performed on a doxorubicin rat skin wound model to observe the mechanism of promoting wound healing of traditional Chinese medicine Zhu Xiang San. Zhuxiang powder is mainly composed of musk and pearl powder, and has the function of retaining skin and skin. The experiment was divided into 4 groups: (1) Control group. (2) Model group. (3) Model + Zhuxiang scattered group. (4) model + Sheng Ji scattered group. On the 4th day before the operation, doxorubicin 8 mg/kg was injected intravenously. Then the skin with a diameter of 1.5 cm was removed from the skin and sterile gauze and 0.25 g/cm2 of drug were applied. The dressing was changed every other day. It was found that the wound area of Zhu Xiang San and Sheng Ji San on the 4th day of the experiment was larger than that of the model group, 2.19±0.58cm~2, 2.04±0.43cm~2, respectively, and the wound surface secretion increased, while the model group was 1.63±0.51cm~2; On the 8th day of the experiment, the wound area of Zhuxiang San group was significantly reduced, being 0.51±0.19cm~2, while that of the model group was