美国费城宾夕法尼亚大学皮肤病学教授艾伯特·克里格曼博士认为:最近变得著名的一种治疗皮肤皱纹的痤疮药物也许能预防皮肤癌,该药就是维甲酸,也叫维生素A酸,一种维生素A的衍生物,即众所周知的商品药物——全反维生素A酸。1988年8月,国际治疗和化妆用品会议上克里格曼博士报道了100名以上患者利用该药,癌症前期的皮肤损伤(光化学角化病)已经消除。底特律的亨利·福特医院的皮肤病学家安妮·克勒史密斯博士也同意此观点。她在15个月内对30名患者使用维甲酸进行治疗研究并且进行了报道,“六个月后,大约降低了20%光化学角化病数量”。 Dr. Albert Kligman, a professor of dermatology at the University of Pennsylvania in Philadelphia, said: A recent acne medicine that has become famous for the treatment of skin wrinkles may prevent skin cancer. The drug is retinoic acid, also known as retinoic acid, A derivative of vitamin A, the well-known commercial drug called all-retinoic acid. In August 1988, at the International Treatment and Cosmetics Conference, Dr. Kligman reported on the use of the drug in more than 100 patients, precancerous skin lesions (photochemical keratosis) have been eliminated. Anne Klee Smith, a dermatologist at Henry Ford Hospital in Detroit, agrees. In a 15-month study of 30 patients treated with tretinoin and reported, she “reduced the number of photochemical keratoses by about 20% after six months.”