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用高分子右旋糖酐（ＨＭＤ，ＭＷ４０万）尾静脉内注射，造成Ｗｉｓｔｅｒ大 鼠微循环内微血栓形成的微循环障碍模型，采用显微电视放大系统观察活体肠系 膜微循环状态，并测定动、静脉混合血中循环内皮细胞数量，分别取其左心室壁、主 动脉和肠系膜制成病理组织切片，观察心、血管内膜病理形态学变化。结果表明，在 活体肠系膜微循环内可见微血栓，有微血栓形成的大鼠均有心肌缺血性改变和心、 血管内膜损害，以及循环内皮细胞（ＣＥＣ）增多，而ＣＥＣ增多程度似与心血管受损 的严重程度呈平行关系。
Microinjection of micro-thrombosis microcirculation in the microcirculation of Wister rats was induced by injecting into the tail vein of macromolecular dextran (HMD, MW 400 000). The microcosmic state of mesenteric microcirculation was observed with a magnifying microscope system and the arterial and venous mixed Circulating endothelial cells in the blood were taken from the left ventricular wall, aorta and mesentery pathological tissue sections were made to observe the pathological changes of heart and endometrial. The results showed that in vivo mesenteric microcirculation can be seen in the micro-thrombus, micro-thrombosis in rats with myocardial ischemia and heart and intimal damage, and increased circulating endothelial cells (CEC), while the degree of CEC increased with The severity of cardiovascular damage was paralleled.