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目的观察汉防己甲素片(tetrandrine,TET)联合金水宝胶囊治疗矽肺的临床疗效。方法选择我院2011年7月~2013年12月收治的矽肺患者112例,随机分为观察组和对照组,每组56例,对照组给予常规抗炎、止咳、平喘等治疗,观察组在对照组基础上给予汉防己甲素和金水宝胶囊。比较两组临床症状以及肺通气功能指标。结果与治疗前比较,两组治疗后临床表现均明显好转,差异具有统计学意义(P<0.05);与对照组治疗后比较,观察组治疗后临床表现好转更加显著,差异具有统计学意义(P<0.05);与对照组治疗后比较,观察组治疗后肺功能指标改善更加明显,差异有统计学意义(P<0.05)。结论汉防己甲素联合金水宝胶囊治疗矽肺具有良好的临床效果。
Objective To observe the clinical efficacy of tetrandrine (TET) combined with Jinshuibao capsule in the treatment of silicosis. Methods A total of 112 patients with silicosis admitted from July 2011 to December 2013 in our hospital were randomly divided into observation group and control group, with 56 cases in each group. The control group was given conventional anti-inflammatory, cough-relieving and anti-asthma treatment. The observation group On the basis of the control group, tetrandrine and Jinshuibao capsules were given. The clinical symptoms and pulmonary function indexes were compared between the two groups. Results Compared with those before treatment, the clinical manifestations of the two groups were significantly improved after treatment, the difference was statistically significant (P <0.05). Compared with the control group after treatment, the clinical manifestations of the observation group improved more significantly after treatment, the difference was statistically significant (P < P <0.05). Compared with the control group after treatment, the improvement of pulmonary function indexes in the observation group was more obvious, the difference was statistically significant (P <0.05). Conclusion Tetrandrine combined with Jinshuibao treatment of silicosis has a good clinical effect.