胰腺癌确诊时70％以上属于晚期,缺乏有效的治疗措施。近几年的大量研究证实血管生成是肿瘤发生的早期事件,也是肿瘤发展和远处转移的必要条件。本文扼要介绍了血管生成与胰腺癌发生、发展的关系及其对胰腺癌诊治的作用,对目前有望用于胰腺癌诊治研究的血管相关因子作简要综述。 More than 70% of the diagnosed cases of pancreatic cancer are advanced, the lack of effective treatment. Numerous studies in recent years have confirmed that angiogenesis is an early event in tumorigenesis and a necessary condition for tumor development and distant metastasis. This article briefly introduced the relationship between angiogenesis and the occurrence and development of pancreatic cancer and its role in the diagnosis and treatment of pancreatic cancer, and briefly reviewed the vascular related factors that are currently expected to be used in the diagnosis and treatment of pancreatic cancer.