用牛和猪眼肌抗原建立了检测眼肌结合抗体（ＥＭｂＡｂ ） 的ＥＬＩＳＡ法。证实甲亢患者血清中存在ＥＭｂＡｂ。通过ＥＭｂＡｂ 特异免疫复合物、补体复合物解离活性抗体依赖的细胞毒或补体介导的细胞毒（ＡＤＣＣ或ＣＭＡＣ） 测定， 以及ＥＭｂＡｂ 与眼肌细胞抗原结合的实验观察， 表明此种ＥＭｂＡｂ 可能在与已受某种因素损伤后的眼肌结合时， 通过ＡＤＣＣ反应加剧眼肌损伤。 An ELISA for the detection of ocular muscle-binding antibodies (EMb-Ab) was established using bovine and porcine ophthalmic antigens. Confirmed hyperthyroidism in patients with serum EMb Ab. The experimental observation that EMbAb-specific immune complexes, complement complex dissociation active antibody-dependent cytotoxicity or complement-mediated cytotoxicity (ADCC or CMAC) assay, and EMbAb binding to ocular myocyte antigen showed that The EMb-Ab may exacerbate ocular muscle damage through the ADCC reaction when it binds to ocular muscles that have been damaged by some factor.