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目的探讨彩色多普勒超声(Color Doppler,CD)在评估2型糖尿病(Type 2diabetes)患者颈动脉中的应用价值及其与患者微量蛋白尿(Microalbuminuria,MB)的相关性。方法 2010年8月~2013年4月期间在我院收治的2型糖尿病患者89例作为研究对象。其中伴有MB者51例,不伴MB者38例,CD检测两组患者颈动脉中膜厚度(IMT)及与MB相关性。结果 MB阳性组患者IMT为1.21±0.24显著高于MB阴性组0.94±0.20,差别有统计学意义(P<0.01);阳性组患者颈动脉粥样硬化斑块发生率显著高于阴性组(P<0.05);MB阳性组患者IMT厚度与尿清蛋白排泄率(UAE)存在相关性rspeasor=0.47(P<0.05),随UAE值增高,IMT值也随之升高。结论 CD可用于评估2型糖尿病MB患者颈动脉狭窄情况,对于UAE显著增高患者,颈动脉IMT显著增加。
Objective To investigate the value of Color Doppler (CD) in evaluating the carotid artery in patients with type 2 diabetes and its relationship with microalbuminuria (MB). Methods A total of 89 type 2 diabetic patients treated in our hospital from August 2010 to April 2013 were selected as the study subjects. Among them, 51 cases were accompanied by MB, 38 cases were not associated with MB. CD was used to detect carotid IMT and MB in both groups. Results The IMT of MB positive group was significantly higher than that of MB negative group (1.21 ± 0.24) (0.94 ± 0.20) (P <0.01), and the incidence of carotid atherosclerosis plaque in positive group was significantly higher than that of negative group (P <0.05). The correlation between IMT thickness and urinary albumin excretion rate (UAE) in MB-positive patients was rspeasor = 0.47 (P <0.05). With the increase of UAE value, the IMT value also increased. Conclusion CD can be used to evaluate carotid stenosis in MB patients with type 2 diabetes mellitus. IMT in carotid artery is significantly increased in patients with significantly increased UAE.