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生物转化是碳水化合物资源高效利用的有效途径。利用转糖基酶和异构化酶将现有的丰富的单糖、寡糖、环糊精等转化为功能性稀有糖、寡糖,为食品、医药、新材料等行业提供新的原料,对于社会经济发展具有明显的推动作用。本文综述了转糖基酶、异构化酶的结构、定向进化、催化过程调控策略等方面的最新研究进展,并就该领域面临的科学问题和发展趋势进行了总结和展望,以期对相关领域研究者有所启发。
Bioconversion is an effective way to efficiently utilize carbohydrate resources. The use of transglycosylase and isomerase enzymes will be the existing rich monosaccharides, oligosaccharides, cyclodextrins and other functions into a rare sugar, oligosaccharides, food, medicine, new materials and other industries with new raw materials, For the social and economic development has a significant role in promoting. This review summarizes recent advances in the research on the structure of transglycosylase, the structure of isomerase, directed evolution, and the strategies for the regulation of the catalytic process. It also summarizes and forecasts the scientific problems and development trends in this field, The researchers have inspired.