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采用反相高效液相色谱法分离了 1 ,1’-联萘 - 2 ,2’-二酚 -单 [(- ) -孟基 ]碳酸酯旋光异构体 .考察了这一对旋光化合物的反相高效液相色谱行为 .结果表明 ,C1 8及 C8柱和醇 /水流动相体系适合于这一对旋光异构体的分离 .进一步优化了色谱分离条件 ,并用于它们的光学纯度测定
The optical isomers of 1, 1’-binaphthyl-2, 2’-diphenol-mono [(-) - mengyl] carbonate were separated by reversed-phase high performance liquid chromatography Reversed-phase high performance liquid chromatography.The results showed that the C1 8 and C8 columns and the alcohol / water mobile phase system were suitable for the separation of this pair of optical isomers.The chromatographic conditions were further optimized and used for their optical purity determination