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为探讨围手术期全肠外营养（ＴＰＮ）在大肠癌病人中的应用价值，我们有选择地对１５例病人围手术期进行ＴＰＮ８～１０ｄ。结果术前病人均有营养不良和细胞免疫功能抑制，术后营养状况明显改善，获得正氮平衡，前白蛋白、转铁蛋白明显增加，细胞免疫功能明显改善，ＣＤ３＋、ＣＤ４＋细胞百分率明显增加，ＣＤ８＋细胞百分率明显下降，ＣＤ４＋／ＣＤ８＋比值明显增加。我们认为围手术期ＴＰＮ能使中、重度营养不良的大肠癌病人受益
To investigate the value of perioperative total parenteral nutrition (TPN) in patients with colorectal cancer, we selectively performed TPN for 8 to 10 days in 15 patients during the perioperative period. Results Preoperative patients had malnutrition and inhibition of cellular immune function. Postoperative nutritional status improved significantly, positive nitrogen balance was obtained, prealbumin and transferrin were significantly increased, cellular immune function was significantly improved, and the percentage of CD3+ and CD4+ cells was significantly increased. The percentage of CD8+ cells decreased significantly, and the ratio of CD4+/CD8+ increased significantly. We believe that perioperative TPN can benefit moderate to severe malnutrition patients with colorectal cancer