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三氟甲基吩噻嗪类化合物具有治疗精神病的作用,因而此类新化合物的合成较受重视。本文报道合成2-氨基-5-三氟甲基苯硫酚(Ⅰ)及将其转变为2-甲氧基-7-三氟甲基吩噻嗪-3-酚(Ⅲ)的简便方法。
Trifluoromethyl phenothiazine compounds have a psychotropic effect, so the synthesis of such new compounds is more valued. This paper reports a simple method for the synthesis of 2-amino-5-trifluoromethylthiophenol (Ⅰ) and its conversion to 2-methoxy-7-trifluoromethylphenothiazine-3-ol.